Which stage of mitosis follows metaphase?

• A. Telophase
• B. Prophase
• C. Interphase
• D. Anaphase

Answer: (D)

The stage that follows metaphase in mitosis is anaphase. During metaphase, the chromosomes align at the cell's equatorial plane, known as the metaphase plate, and are attached to spindle fibers. Following this alignment, anaphase begins when the sister chromatids are pulled apart due to the shortening of the spindle fibers. This process ensures that each daughter cell will receive an identical set of chromosomes. As the sister chromatids are separated and move toward opposite poles of the cell, this is a crucial step in ensuring genetic consistency during cell division. Understanding the sequence of stages in mitosis is essential for grasping how cells replicate and the importance of each phase in maintaining genetic integrity.